The random allocation process: two things you need to know

Good methods of generating a random allocation sequence include using a randomnumbers table or a computer software program that generates the random sequence. There are manual methods of achieving random allocation such as tossing a coin, drawing lots or throwing dice. However, these manual methods in practice often become nonrandom, are difficult to implement and do not leave an audit trail. Therefore, they are not generally recommended. Procedures to avoid completely include using hospital chart numbers, alternating patients sequentially or assigning by date of birth.